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Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins. Interacting selectively and non-covalently with interleukin-1. Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors. Combining with a cytokine to initiate a change in cell activity. Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate. Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response. Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: interleukin-1 receptor activity
Acc: GO:0004908
Aspect: Molecular Function
Desc: Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
Synonyms:
  • IL-1 receptor activity
  • IL-1R
Proteins in PDR annotated with:
   This term: 19 [Search]
   Term or descendants: 21 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004908 - interleukin-1 receptor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle