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Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3. Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group. Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol. Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate. Catalysis of the hydrolysis of a glycerophospholipid. Catalysis of the hydrolysis of a lipid or phospholipid.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phospholipase D activity
Acc: GO:0004630
Aspect: Molecular Function
Desc: Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.
Synonyms:
  • lecithinase D activity
  • choline phosphatase activity
  • phosphatidylcholine phosphatidohydrolase activity
  • lipophosphodiesterase II activity
Proteins in PDR annotated with:
   This term: 36 [Search]
   Term or descendants: 36 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004630 - phospholipase D activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle