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Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: poly(A)-specific ribonuclease activity
Acc: GO:0004535
Aspect: Molecular Function
Desc: Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
Synonyms:
  • 2',3'-exoribonuclease activity
  • poly(A)-specific RNase activity
  • 3'-exoribonuclease activity
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004535 - poly(A)-specific ribonuclease activity (interactive image map)
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