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Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: flavin-containing monooxygenase activity
Acc: GO:0004499
Aspect: Molecular Function
Desc: Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
Synonyms:
  • 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity
  • methylphenyltetrahydropyridine N-monooxygenase activity
  • dimethylaniline monooxygenase (N-oxide-forming) activity
  • FMO activity
  • N,N-dimethylaniline monooxygenase activity
  • DMA oxidase activity
  • FMO1
  • FMO2
  • FMO3
  • FMO4
  • FMO5
  • FMO-II
  • GO:0047076
  • N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)
  • flavin monooxygenase activity
  • mixed-function amine oxidase activity
  • dimethylaniline oxidase activity
  • FAD-containing monooxygenase activity
  • Ziegler's enzyme
  • dimethylaniline N-oxidase activity
  • FMO-I
  • flavin mixed function oxidase activity
Proteins in PDR annotated with:
   This term: 50 [Search]
   Term or descendants: 50 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004499 - flavin-containing monooxygenase activity (interactive image map)
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Created and Maintained by: Michael Riffle