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Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP. Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: methylmalonate-semialdehyde dehydrogenase (acylating) activity
Acc: GO:0004491
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+.
Synonyms:
  • 2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)
  • MSDH activity
  • MMSA dehydrogenase activity
Proteins in PDR annotated with:
   This term: 34 [Search]
   Term or descendants: 34 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004491 - methylmalonate-semialdehyde dehydrogenase (acylating) activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle