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Catalysis of the reaction: trans,trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate. Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: farnesyl-diphosphate farnesyltransferase activity
Acc: GO:0004310
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
Synonyms:
  • farnesyltransferase activity
  • squalene synthase activity
  • presqualene synthase activity
  • squalene synthetase activity
  • farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity
  • presqualene-diphosphate synthase activity
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004310 - farnesyl-diphosphate farnesyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle