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Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate. null Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Acc: GO:0003864
Aspect: Molecular Function
Desc: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
Synonyms:
  • 5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity
  • alpha-ketoisovalerate hydroxymethyltransferase activity
  • 5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity
  • ketopantoate hydroxymethyltransferase activity
  • oxopantoate hydroxymethyltransferase activity
  • dehydropantoate hydroxymethyltransferase activity
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003864 - 3-methyl-2-oxobutanoate hydroxymethyltransferase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle