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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself. Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself. The function of a transcription cofactor that activates transcription from a RNA polymerase II promoter; does not bind DNA itself. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transcription cofactor activity
Acc: GO:0003712
Aspect: Molecular Function
Desc: The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself.
Synonyms:
  • transcriptional cofactor activity
  • transcriptional co-regulator
Proteins in PDR annotated with:
   This term: 126 [Search]
   Term or descendants: 591 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003712 - transcription cofactor activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle