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The multicellular organismal process by which the heart decreases in volume in a characteristic way to propel blood through the body. Any process that modulates the extent of heart contraction, changing the force with which blood is propelled. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body. The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine. The process by which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction. Any process that stops, prevents or reduces the frequency, rate or extent of heart contraction.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of the force of heart contraction by chemical signal
Acc: GO:0003108
Aspect: Biological Process
Desc: Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
Synonyms:
  • negative regulation of the force of heart muscle contraction by chemical signal
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003108 - negative regulation of the force of heart contraction by chemical signal (interactive image map)

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