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A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil. Any process of the immune system that occurs as part of an immune response. The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors. Any process involved in the carrying out of an immune response by a myeloid leukocyte. Any process involved in the carrying out of an immune response by a basophil. A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. The regulated exocytosis of secretory granules by a leukocyte. The regulated release of serotonin by a basophil or group of basophils. The regulated release of histamine by a basophil or group of basophils.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: basophil degranulation
Acc: GO:0002561
Aspect: Biological Process
Desc: The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002561 - basophil degranulation (interactive image map)
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Created and Maintained by: Michael Riffle