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Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity. An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes. Any process that activates or increases the frequency, rate, or extent of hypersensitivity. An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue. An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors. Any process that modulates the frequency, rate, or extent of hypersensitivity. An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines. An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hypersensitivity
Acc: GO:0002524
Aspect: Biological Process
Desc: An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
Synonyms:
  • hypersensitivity response
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 26 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002524 - hypersensitivity (interactive image map)
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