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The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I. Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: antigen processing and presentation of peptide antigen via MHC class I
Acc: GO:0002474
Aspect: Biological Process
Desc: The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
Synonyms:
  • peptide antigen processing and presentation via MHC class I
Proteins in PDR annotated with:
   This term: 102 [Search]
   Term or descendants: 122 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002474 - antigen processing and presentation of peptide antigen via MHC class I (interactive image map)
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Created and Maintained by: Michael Riffle