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The directed killing of a target cell by a leukocyte. An immune response mediated by a T cell triggered in response to the presence of a tumor cell. Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target. An immune system process that functions in the response of an organism to a tumor cell. The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. A process that directly activates any of the steps required for cell death by apoptosis. Any process involved in the carrying out of an immune response by a T cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: T cell mediated cytotoxicity directed against tumor cell target
Acc: GO:0002419
Aspect: Biological Process
Desc: The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
Synonyms:
  • T lymphocyte mediated cytotoxicity directed against tumor cell target
  • T-cell mediated cytotoxicity directed against tumor cell target
  • T-lymphocyte mediated cytotoxicity directed against tumor cell target
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002419 - T cell mediated cytotoxicity directed against tumor cell target (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle