YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process by which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells. The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. The process whereby a relatively unspecialized precursor cell acquires specialized features of B cells, T cells, or natural killer cells. The process by which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell. The process by which a lymphoid progenitor cell becomes committed to becoming any type of T cell. The process whereby a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes. The process by which a pro-T cell becomes committed to becoming a gamma-delta T cell. The process by which a pro-T cell becomes committed to becoming an NK T cell. The process by which a pro-T cell becomes committed to becoming an alpha-beta T cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: T cell lineage commitment
Acc: GO:0002360
Aspect: Biological Process
Desc: The process by which a lymphoid progenitor cell becomes committed to becoming any type of T cell.
Synonyms:
  • T lymphocyte lineage commitment
  • T-cell lineage commitment
  • T-lymphocyte lineage commitment
Proteins in PDR annotated with:
   This term: 18 [Search]
   Term or descendants: 19 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002360 - T cell lineage commitment (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle