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The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival. Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process by which B or T cells are selected to survive based on signaling through their antigen receptors. The process whereby a precursor cell type acquires the specialized features of a B cell. The deletion of B cells by apoptosis occurring as part of central tolerance induction and B cell selection. Any process leading to negative selection of B cells in the bone marrow. Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow. Any B cell selection process that occurs in the bone marrow. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: central B cell selection
Acc: GO:0002340
Aspect: Biological Process
Desc: Any B cell selection process that occurs in the bone marrow.
Synonyms:
  • central B lymphocyte selection
  • central B-lymphocyte selection
  • central B-cell selection
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002340 - central B cell selection (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle