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An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory). Any process that modulates the frequency, rate, or extent of an adaptive immune response. Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus. An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae). Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: adaptive immune response
Acc: GO:0002250
Aspect: Biological Process
Desc: An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
Synonyms:
  • acquired immune response
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 261 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002250 - adaptive immune response (interactive image map)
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