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The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response. The somatic process by which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of an immune response. An immune response mediated by immunoglobulins, whether cell-bound or in solution. Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of an immune response. The process by which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of an immune response. The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels. The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences. The somatic process by means of which sequence diversity of immunoglobulins is generated. The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: somatic diversification of immunoglobulins during immune response
Acc: GO:0002208
Aspect: Biological Process
Desc: The somatic process by means of which sequence diversity of immunoglobulins is generated after the induction of an immune response.
Synonyms:
  • somatic diversification of antibodies during immune response
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 46 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002208 - somatic diversification of immunoglobulins during immune response (interactive image map)
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