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An immune response mediated by immunoglobulins, whether cell-bound or in solution. An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell. Any process involved in the carrying out of an immune response by a myeloid leukocyte. An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors. Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response. Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response. Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response. Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: type IIa hypersensitivity
Acc: GO:0001794
Aspect: Biological Process
Desc: An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001794 - type IIa hypersensitivity (interactive image map)
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