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The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2. The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure. The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: prostaglandin biosynthetic process
Acc: GO:0001516
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
Synonyms:
  • prostaglandin biosynthesis
  • prostaglandin anabolism
  • prostaglandin synthesis
  • prostaglandin formation
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 36 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001516 - prostaglandin biosynthetic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle