YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. The process, arising in dividing cells as they age, that alters cellular metabolism and thus causes a decline in cell function. A change in state or activity of a cell or an organism occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism. Progression of the cell from its inception to the end of its lifespan. The inherent decline over time, from the optimal fertility and viability of early maturity, that may precede death and may be preceded by other indications, such as sterility. The process arising as the cell progresses toward the end of its lifespan that cause changes cellular metabolism, resulting in a decline in cell function; for example, a decline in the efficiency of protein synthesis. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: age-dependent general metabolic decline involved in replicative cell aging
Acc: GO:0001321
Aspect: Biological Process
Desc: The process, arising in dividing cells as they age, that alters cellular metabolism and thus causes a decline in cell function.
Synonyms:
  • age-dependent general metabolic decline during replicative cell ageing
  • age-dependent general metabolic decline involved in replicative cell aging
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001321 - age-dependent general metabolic decline involved in replicative cell aging (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle