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The cellular metabolic process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template during gene conversion at the mating-type locus. The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template. The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template. The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA synthesis involved in DNA repair
Acc: GO:0000731
Aspect: Biological Process
Desc: Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template.
Synonyms:
  • DNA synthesis during DNA repair
  • DNA repair synthesis
Proteins in PDR annotated with:
   This term: 22 [Search]
   Term or descendants: 30 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000731 - DNA synthesis involved in DNA repair (interactive image map)
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