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A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. The nucleic acid metabolic process by which the phosphodiester bonds between nucleotides are cleaved by hydrolysis. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any cellular metabolic process involving nucleic acids. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism. The site-specific endonucleolytic cleavage of DNA at the mating-type locus which initiates the conversion of one mating-type allele to another. The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus. The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged. The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: gene conversion at mating-type locus, DNA double-strand break formation
Acc: GO:0000728
Aspect: Biological Process
Desc: The site-specific endonucleolytic cleavage of DNA at the mating-type locus which initiates the conversion of one mating-type allele to another.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000728 - gene conversion at mating-type locus, DNA double-strand break formation (interactive image map)
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