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The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. Splicing of RNA via a series of two transesterification reactions. Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile. Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: RNA splicing, via transesterification reactions
Acc: GO:0000375
Aspect: Biological Process
Desc: Splicing of RNA via a series of two transesterification reactions.
Synonyms:
  • GO:0000385
  • spliceosomal catalysis
  • pre-mRNA splicing factor activity
  • RNA splicing factor activity, transesterification mechanism
  • GO:0031202
Proteins in PDR annotated with:
   This term: 45 [Search]
   Term or descendants: 869 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000375 - RNA splicing, via transesterification reactions (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle