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Interacting selectively and non-covalently with a 7-methylguanosine (m7G) moiety or derivative located at the 5' end of an RNA molecule. Interacting selectively and non-covalently with an RNA molecule or a portion thereof. Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) moiety located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans. Interacting selectively and non-covalently with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa. Interacting selectively and non-covalently with the 7-methylguanosine moiety added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II. Interacting selectively and non-covalently with any nucleic acid.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: RNA cap binding
Acc: GO:0000339
Aspect: Molecular Function
Desc: Interacting selectively and non-covalently with a 7-methylguanosine (m7G) moiety or derivative located at the 5' end of an RNA molecule.
Synonyms:
  • binding to mRNA cap
  • mRNA cap binding
  • snRNA cap binding
Proteins in PDR annotated with:
   This term: 27 [Search]
   Term or descendants: 39 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000339 - RNA cap binding (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle