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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule. Any process that stops, prevents or reduces the frequency, rate or extent of DNA transposition. Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites. Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. Any process involved in a type of transpositional recombination which occurs via a DNA intermediate. Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombination.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of transposition, DNA-mediated
Acc: GO:0000335
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of DNA transposition.
Synonyms:
  • down-regulation of DNA transposition
  • down regulation of DNA transposition
  • negative regulation of DNA transposition
  • downregulation of DNA transposition
  • inhibition of DNA transposition
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000335 - negative regulation of transposition, DNA-mediated (interactive image map)
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