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The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. Cyclin-dependent protein kinase (CDK) complex found in the nucleus. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. Cyclin-dependent protein kinases (CDKs) are heterodimeric enzymes that contain a kinase catalytic subunit associated with a regulatory cyclin partner. Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm. Any constituent part of a cell, the basic structural and functional unit of all organisms. A protein complex that activates cyclin-dependent kinase 5; composed of regulatory and catalytic subunits. A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC). Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cyclin-dependent protein kinase holoenzyme complex
Acc: GO:0000307
Aspect: Cellular Component
Desc: Cyclin-dependent protein kinases (CDKs) are heterodimeric enzymes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
Synonyms:
  • CDK holoenzyme
Proteins in PDR annotated with:
   This term: 43 [Search]
   Term or descendants: 67 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000307 - cyclin-dependent protein kinase holoenzyme complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle