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Catalysis of the transfer of a functional group from one position to another within a single molecule. Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus. Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: lanosterol synthase activity
Acc: GO:0000250
Aspect: Molecular Function
Desc: Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.
Synonyms:
  • squalene 2,3-epoxide:lanosterol cyclase activity
  • 2,3-oxidosqualene-lanosterol cyclase activity
  • squalene-2,3-oxide-lanosterol cyclase activity
  • 2,3-epoxysqualene--lanosterol cyclase activity
  • 2,3-oxidosqualene sterol cyclase activity
  • lanosterol 2,3-oxidosqualene cyclase activity
  • oxidosqualene-lanosterol cyclase activity
  • (S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)
  • oxidosqualene--lanosterol cyclase activity
  • squalene epoxidase-cyclase activity
  • 2,3-epoxysqualene lanosterol cyclase activity
  • 2,3-epoxysqualene-lanosterol cyclase activity
  • OSC
  • oxidosqualene:lanosterol cyclase activity
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000250 - lanosterol synthase activity (interactive image map)
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