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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.945367738221]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
BUD6
  • polarisome
  • actin cap
    		•
  • cellular bud site selection
  • bipolar cellular bud site selection
  • response to osmotic stress
  • cytokinesis
  • actin filament organization
  • Rho protein signal transduction
    		•
  • cytoskeletal regulatory protein binding
    		•
    SRV2
  • actin cortical patch
    		•
  • cytoskeleton organization
  • pseudohyphal growth
  • Ras protein signal transduction
    		•
  • adenylate cyclase binding
  • cytoskeletal protein binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cortical actin cytoskeleton 6.6999E-5 2 52 2 6292
    cortical cytoskeleton 6.6999E-5 2 52 2 6292
    actin cytoskeleton 1.8038E-4 2 85 2 6292
    cell cortex part 2.304E-4 2 96 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292
    polarisome 1.9064E-3 2 6 1 6292
    actin cap 3.811E-3 2 12 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Ras protein signal transduction 4.1432E-5 2 41 2 6292
    small GTPase mediated signal transduction 1.0186E-4 2 64 2 6292
    intracellular signal transduction 3.312E-4 2 115 2 6292
    intracellular signaling pathway 5.2022E-4 2 144 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    signaling 1.598E-3 2 252 2 6292
    Rho protein signal transduction 6.3477E-3 2 20 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cytoskeletal protein binding 8.6451E-5 2 59 2 6292
    adenylate cyclase binding 3.1786E-4 2 1 1 6292
    cytoskeletal regulatory protein binding 1.9064E-3 2 6 1 6292
    enzyme binding 4.4455E-3 2 14 1 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle