From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.637047075585] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
peripheral to membrane of membrane fraction | 4.5979E-6 | 2 | 14 | 2 | 6292 |
membrane fraction | 2.0691E-4 | 2 | 91 | 2 | 6292 |
insoluble fraction | 2.0691E-4 | 2 | 91 | 2 | 6292 |
cell fraction | 4.1715E-4 | 2 | 129 | 2 | 6292 |
internal side of plasma membrane | 1.5888E-3 | 2 | 5 | 1 | 6292 |
extrinsic to internal side of plasma membrane | 1.5888E-3 | 2 | 5 | 1 | 6292 |
TORC1 complex | 1.9064E-3 | 2 | 6 | 1 | 6292 |
TORC2 complex | 2.859E-3 | 2 | 9 | 1 | 6292 |
extrinsic to plasma membrane | 5.3968E-3 | 2 | 17 | 1 | 6292 |
endosomal part | 7.2981E-3 | 2 | 23 | 1 | 6292 |
endosome membrane | 7.2981E-3 | 2 | 23 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
actin cytoskeleton organization | 3.1973E-4 | 2 | 113 | 2 | 6292 |
actin filament-based process | 3.4287E-4 | 2 | 117 | 2 | 6292 |
cytoskeleton organization | 1.3422E-3 | 2 | 231 | 2 | 6292 |
mitochondria-nucleus signaling pathway | 2.224E-3 | 2 | 7 | 1 | 6292 |
protein secretion | 2.859E-3 | 2 | 9 | 1 | 6292 |
establishment or maintenance of actin cytoskeleton polarity | 2.859E-3 | 2 | 9 | 1 | 6292 |
establishment or maintenance of cytoskeleton polarity | 2.859E-3 | 2 | 9 | 1 | 6292 |
fungal-type cell wall organization | 3.4937E-3 | 2 | 11 | 1 | 6292 |
regulation of cell growth | 3.811E-3 | 2 | 12 | 1 | 6292 |
regulation of growth | 4.4455E-3 | 2 | 14 | 1 | 6292 |
cortical actin cytoskeleton organization | 4.7627E-3 | 2 | 15 | 1 | 6292 |
cortical cytoskeleton organization | 4.7627E-3 | 2 | 15 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein kinase activator activity | 2.859E-3 | 2 | 9 | 1 | 6292 |
kinase activator activity | 3.1764E-3 | 2 | 10 | 1 | 6292 |
protein binding | 9.4468E-3 | 2 | 612 | 2 | 6292 |