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Protein Overview: YNL247W

General Information:
Name(s) found: YNL247W [SGD]
Description(s) found:
Found 31 descriptions.
SHOW ALL
  • Cysteinyl-tRNA synthetase; may interact with ribosomes, based on co-purification experiments [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 767 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    cysteine metabolic process [NASLink to PubMed article]
    cysteinyl-tRNA aminoacylation [IDALink to PubMed article]
    Molecular Function: cysteine-tRNA ligase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIFIKALRR YTIMSTPKIV QPKWKVPTPQ AKETVLKLYN SLTRSKVEFI PQSGNRGVTW  60
   61 YSCGPTVYDA SHMGHARNYV SIDINRRIIQ DYFGYDVQFV QNVTDIDDKI ILRARQNYLF 120
  121 DNFVKENDTK FNATVVDKVK TALFQYINKN FTIQGSEIKT IEEFETWLSN ADTETLKLEN 180
  181 PKFPMHVTAV QNAIESITKG DSMDAEVAFE KVKDVTVPLL DKELGSTISN PEIFRQLPAY 240
  241 WEQKFNDDML SLNVLPPTVT TRVSEYVPEI IDFVQKIIDN GYAYATSDGS VYFDTLKFDK 300
  301 SPNHDYAKCQ PWNKGQLDLI NDGEGSLSNF ADNGKKSNND FALWKASKAG EPEWESPWGK 360
  361 GRPGWHIECS VMASDILGSN IDIHSGGIDL AFPHHDNELA QSEARFDNQQ WINYFLHTGH 420
  421 LHIEGQKMSK SLKNFITIQE ALKKFSPRQL RLAFASVQWN NQLDFKESLI HEVKSFENSM 480
  481 NNFFKTIRAL KNDAASAGHI SKKFSPLEKE LLADFVESES KVHSAFCDNL STPVALKTLS 540
  541 ELVTKSNTYI TTAGAALKIE PLIAICSYIT KILRIIGFPS RPDNLGWAAQ AGSNDGSLGS 600
  601 LEDTVMPYVK CLSTFRDDVR SLAIKKAEPK EFLQLTDKIR NEDLLNLNVA LDDRNGQSAL 660
  661 IKFLTNDEKL EIVKLNEEKH ANELAKKQKK LEQQKLREQK ENERKQKAQI KPQDMFKDVT 720
  721 LYSAWDEQGL PTKDKDGNDI TKSMTKKLKK QWEQQKKLHE EYFGEDK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GSP1 SRM1 YNL247W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MLC1 YNL247W 2 Unpublished Fields Lab Data
    View Screen DCN1 YNL247W 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YNL247W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] PSI-BLAST 2.045757 No description for 1lleA_ was found.
    2 View Details [154..419] PSI-BLAST 588.54902 Cysteinyl-tRNA synthetase (CysRS)
    3 View Details [420..474] PSI-BLAST 588.54902 Cysteinyl-tRNA synthetase (CysRS)
    4 View Details [475..664] PSI-BLAST 588.54902 Cysteinyl-tRNA synthetase (CysRS)
    5 View Details [665..767] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  5.23703961447809 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  3.76808520367507 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.89131347796645 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.369886886936128 bayes_pls_golite062009
  • RNA binding
    		•  0.306683553109855 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009
  • binding
    		•  0.090743795600025 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle