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Protein Overview: FRE6

General Information:
Name(s) found: FRE6 / YLL051C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 712 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: ferric-chelate reductase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRTLLFLTW LISLTKAFNI KLPHTEKKDH LESNAVLACA SYINTLKWSF DSSVVPGFYS  60
   61 TICSYSPAFD TWSLCIFNSL TDQIIPMDNT SFEESLGNVR KTCSFVDKKF SNISLEQYYS 120
  121 SLNNASSHAL EDYGSIESLS TSIRVDRETR SRWIRAFHAH AYNLDISSVY GAYLTYYFVI 180
  181 VGIIAVFFHM SHYNGLNRAL FASRFVNYIR GHFVLPTFLV DKHANHFKFL NVEVFTGLMP 240
  241 NSLEAWIIFG YTLANIIFLS ISYIIDPYNL IFNSHLSQFT RLLADRSGIL AFTQFPLIII 300
  301 FTARNSFLEF LTGVKFNSFI SFHKWIGRIM VLNATIHSLS YSLFAIINHA FKISNKQLYW 360
  361 KFGIASITVL CVLLVLSLGI VRKRHYEFFL YTHIILALLF FYCCWQHVKI FNGWKEWIVV 420
  421 SLLIWGLEKL FRIWNILQFR FPKATLINLN TSNNPHDEMF KVIIPKYNRR WHSKPGQYCF 480
  481 IYFLHPLVFW QCHPFTIIDE GEKCVLVIKP KSGLTRFIYN HILQSLNGKL QLRVAIEGPY 540
  541 GPSNLHLDKF DHLLLLSGGT GLPGPLDHAI KLSRNPDKPK SIDLIMAIKN PSFLNGYKSE 600
  601 ILELKNSRSH VNVQVYLTQK TAVTKAANAR DQLIHFDDIM TELTSFAHIG NARPNFSNVI 660
  661 ENAIKSTPPG DSLAVVCCGP PVLVDDVRNT VSQKLLGYPE RIIEYFEEYQ CW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data FRE6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..272] deduced N/A No confident structure predictions are available.
    2 View Details [273..422] MSA 2.154983 View MSA. Confident ab initio structure predictions are available.
    3 View Details [423..540] PSI-BLAST 52.69897 Nitrate reductase core domain; Nitrate reductase
    4 View Details [541..712] PSI-BLAST 52.69897 Nitrate reductase core domain; Nitrate reductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.13408475648113 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.58197349520772 bayes_pls_golite062009
  • protein binding
    		•  0.144900113694048 bayes_pls_golite062009
  • cofactor binding
    		•  0.0731141170494622 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle