Protein Overview: Notum-PA

General Information:
Name(s) found:	Notum-PA / FBpp0075193 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45551565\|ref\|NP_730096.2\| notum, isoform A [Drosophila melanogaster] [NCBI NR] gi\|45445861\|gb\|AAF49550.3\| notum, isoform A [Drosophila melanogaster] [NCBI NR] gi\|20805945\|gb\|AAL85497.1\| wingful [Drosophila melanogaster] [NCBI NR] gi\|20269077\|emb\|CAD29885.1\| Notum protein [Drosophila melanogaster] [NCBI NR] Palmitoleoyl-protein carboxylesterase NOTUM OS=Drosophila melanogaster GN=Notum PE=1 SV=3 [Swiss-Prot] The gene Notum is referred to in FlyBase by the symbol Dmel\Notum (CG13076, FBgn0044028). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16016580..16025861. It has the cytological map location 72C3-72D1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of compound eye pigmentation; GPI anchor release; wing disc dorsal/ventral pattern formation; Wnt receptor signaling pathway. 24 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; leg; dorsal mesothoracic disc; wing margin bristle; denticle row 1; mesothoracic tergum; dorsal row; wing; denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] (AAF49550) CG13076-PA [DrosMelano7227.FASTAC.txt] CG13076-PA, isoform A [Drosophila melanogaster]gi\|20805945\|gb\|AAL85497.1\| wingful [Drosophila melanogaster]gi\|45551565\|ref\|NP_730096.2\| CG13076-PA [Drosophila melanogaster]gi\|20269077\|emb\|CAD29885.1\| Notum protein [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(16016945..16017019,16022371..16022764,16022831..16023343,16023408..16024441); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotatio [fly-100309-contam.fasta] Notum protein [Drosophila melanogaster] [nr-271106-contam.fasta] wingful [Drosophila melanogaster] [nr-271106-contam.fasta] CG13076-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Notum CG13076-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(16016945..16017019,16022371..16022764,16022831..16023343,16023408..16024441); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(16016945..16017019,16022371..16022764,16022831..16023343,16023408..16024441); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Notum protein OS=Drosophila melanogaster GN=Notum PE=2 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(16016945..16017019,16022371..16022764,16022831..16023343,16023408..16024441); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550,FlyMine:FBpp0075193,modMine:FBpp0075193; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(16023845..16023919,16029271..16029664,16029731..16030243,16030308..16031341); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550,FlyMine:FBpp0075193,modMine:FBpp0075193; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(16023845..16023919,16029271..16029664,16029731..16030243,16030308..16031341); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550,FlyMine:FBpp0075193,modMine:FBpp0075193; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0075193 type=protein; loc=3L:join(16023845..16023919,16029271..16029664,16029731..16030243,16030308..16031341); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550,FlyMine:FBpp0075193,modMine:FBpp0075193; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(16023845..16023919,16029271..16029664,16029731..16030243,16030308..16031341); ID=FBpp0075193; name=Notum-PA; parent=FBgn0044028,FBtr0075435; dbxref=GB_protein:AAF49550.3,GB_protein:AAF49550.2,FlyBase:FBpp0075193,FlyBase_Annotation_IDs:CG13076-PA,REFSEQ:NP_730096,GB_protein:AAF49550,UniProt/Swiss-Prot:Q9VUX3,FlyMine:FBpp0075193,modMine:FBpp0075193; MD5=66860f384c8c76770d2b2f73a8b412de; length=671; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	671 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IDA]
Biological Process:	regulation of compound eye pigmentation [IMP] GPI anchor release [IMP] Wnt receptor signaling pathway [IMP][NAS] wing disc dorsal/ventral pattern formation [IGI] negative regulation of Wnt receptor signaling pathway [NAS] proteoglycan metabolic process [NAS]
Molecular Function:	[NOT]deacetylase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVEQIDKMA AKAGEATNKW IKPQQPLLTL LLLLATFSQL PAVCSSSILD AASLQEKDPL  60
   61 RDTSMNMIQR NYMVMHSASG SGDHSRSLKR ANLANTSITC NDGSHAGFYL RKHPSSKKWI 120
  121 VLLEGGWHCF DVRSCRSRWM RLRHLMTSSQ WPETRDVGGI LSPHPEENPY WHNANHVLIP 180
  181 YCSSDSWSGT RTEPDTSDRE NSWRFMGALI LRQVIAELIP VGLGRVPGGE LMLVGSSAGG 240
  241 MGVMLNLDRI RDFLVNEKKL QITVRGVSDS GWFLDREPYT PAAVASNEAV RQGWKLWQGL 300
  301 LPEECTKSYP TEPWRCYYGY RLYPTLKTPL FVFQWLFDEA QMRVDNVGAP VTPQQWNYIH 360
  361 EMGGALRSSL DNVSAVFAPS CIGHGVLFKR DWVNIKIDDI SLPSALRCWE HSTRSRRHDK 420
  421 LKRSTEPSTA VSHPEHANNQ RHQRHRQRLQ RQKHNNVAQS GGQQRKHNHL SKEEREERKR 480
  481 LRQEQRQRRK QRRRQQQQKK ANGGQEHRNK KDNSPKSSNG NDQRKQRRRQ QLTAEERQEQ 540
  541 RKRRRKAQQQ QMKMQREQPA AGVFLEASAP QKTRSSNNAS AGTKSKKRHR VPRVPEKCGL 600
  601 RLLERCSWPQ CNHSCPTLTN PMTGEEMRFL ELLTAFGLDI EAVAAALGVD MHTLNNMERT 660
  661 ELVNMLTQQA N

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Notum-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: