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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that modulates the frequency, rate or extent of a signaling pathway. Any process that modulates the frequency, rate or extent of the activity of the Wnt receptor mediated signal transduction pathway. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis. Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that stops, prevents or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC). The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state. Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of Wnt receptor signaling pathway
Acc: GO:0030178
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity.
Synonyms:
  • down-regulation of Wnt receptor signaling pathway
  • down regulation of Wnt receptor signaling pathway
  • negative regulation of frizzled signalling pathway
  • downregulation of frizzled signaling pathway
  • downregulation of Wnt receptor signaling pathway
  • inhibition of frizzled signaling pathway
  • down-regulation of frizzled signaling pathway
  • inhibition of Wnt receptor signaling pathway
  • negative regulation of Wnt receptor signalling pathway
  • down regulation of frizzled signaling pathway
  • negative regulation of frizzled signaling pathway
  • GO:0045810
Proteins in PDR annotated with:
   This term: 96 [Search]
   Term or descendants: 107 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030178 - negative regulation of Wnt receptor signaling pathway (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle