General Information: |
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Name(s) found: |
PAX6_RAT
[Swiss-Prot]
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Description(s) found:
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Organism: | Rattus norvegicus |
Length: | 422 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[IC][UNKNOWN][IDA][IEA]
cytoplasm [UNKNOWN] intracellular part [UNKNOWN] intracellular [UNKNOWN] |
Biological Process: |
regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment
[UNKNOWN]
multicellular organismal development [IEA] regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification [UNKNOWN] response to wounding [UNKNOWN] anterior/posterior pattern formation [UNKNOWN] forebrain anterior/posterior pattern formation [UNKNOWN] negative regulation of neuron differentiation [UNKNOWN] transcription from RNA polymerase II promoter [IMP] axon guidance [UNKNOWN] forebrain dorsal/ventral pattern formation [UNKNOWN] dorsal/ventral axis specification [UNKNOWN] oligodendrocyte cell fate specification [UNKNOWN] regulation of neuron differentiation [IDA] lens development in camera-type eye [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] salivary gland morphogenesis [UNKNOWN] dorsal/ventral pattern formation [UNKNOWN] neuron migration [UNKNOWN][IMP] forebrain development [UNKNOWN] hindbrain development [IDA] lacrimal gland development [UNKNOWN] axonogenesis [UNKNOWN] camera-type eye development [UNKNOWN] regulation of epithelial cell proliferation [IMP] cell fate determination [UNKNOWN] forebrain-midbrain boundary formation [UNKNOWN] astrocyte differentiation [UNKNOWN] commitment of a neuronal cell to a specific type of neuron in the forebrain [UNKNOWN] eye photoreceptor cell development [UNKNOWN] positive regulation of cell fate specification [IMP] positive regulation of neuroblast proliferation [UNKNOWN] regulation of transcription, DNA-dependent [IEA] smoothened signaling pathway [UNKNOWN] brain development [UNKNOWN][IMP] pallium development [UNKNOWN] pituitary gland development [UNKNOWN] regulation of timing of cell differentiation [UNKNOWN] keratinocyte differentiation [UNKNOWN] positive regulation of epithelial cell differentiation [UNKNOWN] cell fate commitment [UNKNOWN] negative regulation of epithelial cell proliferation [UNKNOWN] regulation of gene expression [UNKNOWN] cell differentiation [UNKNOWN][IEA] protein localization in organelle [UNKNOWN] regulation of cell migration [UNKNOWN] regulation of neurogenesis [UNKNOWN][IMP] |
Molecular Function: |
DNA binding
[UNKNOWN]
transcription factor activity [UNKNOWN][IEA][TAS] protein binding [UNKNOWN] RNA polymerase II transcription factor activity [IMP] double-stranded DNA binding [IDA] AT DNA binding [IDA] sequence-specific DNA binding [IDA][IEA][RCA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MQNSHSGVNQ LGGVFVNGRP LPDSTRQKIV ELAHSGARPC DISRILQVSN GCVSKILGRY 60 61 YETGSIRPRA IGGSKPRVAT PEVVSKIAQY KRECPSIFAW EIRDRLLSEG VCTNDNIPSV 120 121 SSINRVLRNL ASEKQQMGAD GMYDKLRMLN GQTGSWGTRP GWYPGTSVPG QPTQDGCQQQ 180 181 EGQGENTNSI SSNGEDSDEA QMRLQLKRKL QRNRTSFTQE QIEALEKEFE RTHYPDVFAR 240 241 ERLAAKIDLP EARIQVWFSN RRAKWRREEK LRNQRRQASN TPSHIPISSS FSTSVYQPIP 300 301 QPTTPVSSFT SGSMLGRTDT ALTNTYSALP PMPSFTMANN LPMQPPVPSQ TSSYSCMLPT 360 361 SPSVNGRSYD TYTPPHMQTH MNSQPMGTSG TTSTGLISPG VSVPVQVPGS EPDMSQYWPR 420 421 LQ |
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.97 |
Source: Reynolds et al. (2008)