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Protein Overview: KPY1_ECOLI, KPYK...

General Information:
Name(s) found: KPYK1_ECOLI [Swiss-Prot]
KPY1_ECOLI [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Pyruvate kinase I (EC 2.7.1.40) (PK-1) - Escherichia coli [Swiss-Prot]
  • (P14178) Pyruvate kinase I (EC 2.7.1.40) (PK-1) [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 470 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTKIVCTI GPKTESEEML AKMLDAGMNV MRLNFSHGDY AEHGQRIQNL RNVMSKTGKT  60
   61 AAILLDTKGP EIRTMKLEGG NDVSLKAGQT FTFTTDKSVI GNSEMVAVTY EGFTTDLSVG 120
  121 NTVLVDDGLI GMEVTAIEGN KVICKVLNNG DLGENKGVNL PGVSIALPAL AEKDKQDLIF 180
  181 GCEQGVDFVA ASFIRKRSDV IEIREHLKAH GGENIHIISK IENQEGLNNF DEILEASDGI 240
  241 MVARGDLGVE IPVEEVIFAQ KMMIEKCIRA RKVVITATQM LDSMIKNPRP TRAEAGDVAN 300
  301 AILDGTDAVM LSGESAKGKY PLEAVSIMAT ICERTDRVMN SRLEFNNDNR KLRITEAVCR 360
  361 GAVETAEKLD APLIVVATQG GKSARAVRKY FPDATILALT TNEKTAHQLV LSKGVVPQLV 420
  421 KEITSTDDFY RLGKELALQS GLAHKGDVVV MVSGALVPSG TTNTASVHVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..470] PSI-BLAST 162.0 Pyruvate kinase (PK); Pyruvate kinase, N-terminal domain; Pyruvate kinase, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyruvate kinase activity
    		•  5.30539631424432 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.74686803828771 bayes_pls_golite062009
  • kinase activity
    		•  3.60311146880852 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.2602140947877 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.49386405838309 bayes_pls_golite062009
  • transferase activity
    		•  2.39042747917065 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.35681897894387 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  1.41686595651633 bayes_pls_golite062009
  • binding
    		•  1.40856686140554 bayes_pls_golite062009
  • ADP binding
    		•  1.23883289666587 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  1.09759860844913 bayes_pls_golite062009
  • hydrolase activity
    		•  0.962445116339459 bayes_pls_golite062009
  • catalytic activity
    		•  0.932947046865376 bayes_pls_golite062009
  • phosphoenolpyruvate carboxykinase activity
    		•  0.777178963260734 bayes_pls_golite062009
  • protein binding
    		•  0.438735017993357 bayes_pls_golite062009
  • lyase activity
    		•  0.0456521871650777 bayes_pls_golite062009
  • phosphotransferase activity, paired acceptors
    		•  0.0254711315719321 bayes_pls_golite062009
  • citrate (pro-3S)-lyase activity
    		•  0.0039163158887896 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle