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Protein Overview: ISPF_ECOLI

General Information:
Name(s) found: ISPF_ECOLI [Swiss-Prot]
Description(s) found:
Found 44 descriptions.
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  • 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (EC 4.6.1.12) (MECPS) (MECDP-synthase) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 159 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIGHGFDVH AFGGEGPIII GGVRIPYEKG LLAHSDGDVA LHALTDALLG AAALGDIGKL  60
   61 FPDTDPAFKG ADSRELLREA WRRIQAKGYT LGNVDVTIIA QAPKMLPHIP QMRVFIAEDL 120
  121 GCHMDDVNVK ATTTEKLGFT GRGEGIACEA VALLIKATK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 70.39794 Structures of MECP synthase in complex with (i) CMP and (ii) CMP and product

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
    		•  5.90222038729348 bayes_pls_golite062009
  • phosphorus-oxygen lyase activity
    		•  3.82238498158628 bayes_pls_golite062009
  • catalytic activity
    		•  1.89592759292365 bayes_pls_golite062009
  • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
    		•  1.55973202658962 bayes_pls_golite062009
  • lyase activity
    		•  1.47817320758946 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle