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Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. Catalysis of the reaction: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP. Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Acc: GO:0008685
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP.
Synonyms:
  • MECDP-synthase activity
  • 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)
  • MECP synthase activity
  • 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)
Proteins in PDR annotated with:
   This term: 12 [Search]
   Term or descendants: 12 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008685 - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity (interactive image map)
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