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Protein Overview: dgk-2

General Information:
Name(s) found: dgk-2 / CE34027 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00000959 locus:dgk-2 status:Confirmed UniProt:H2KYI9 protein_id:CCD63476.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEALink to PubMed article]
    Molecular Function: diacylglycerol kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMDVYDELL AAALFIVFSS IVLWVFRKLW AVRKRKNIND TSSKSGHYWS SINYSEQHNY  60
   61 CSGCKEHIVS GYECDNCLLK VDNINCLRAV STKIQCKVNP IHCRKETFDH HWICGNIGAD 120
  121 LFCEVCEELC GGVGLQDFRC SWCWRVVHTK CKPKFTKHCD FGGLKRTIIP PYCVTTRRPG 180
  181 NRNQRMAVID KIEIPVDIEK WRPIMVIVNP KSGSGAGKQL LRNFRAHLHP AQVVDVLKSN 240
  241 IAASLRWIDE HPNVDVRILI AGGDGTICSA LDQIDTLSRR IPVAVLPLGT GNDLSRLLKW 300
  301 GKKCDGDIDV IKLMEDIQEA EVTLVDRWTI DAESQKKLGV RLQSNKTLSM TNYVSVGVDA 360
  361 CVTLGMQNTR ESIPRAMSSR LLNKFLFFTF GTKDVFERVC KGLNERIDLY LDDVHVNLPD 420
  421 IEGLIFLNIP YWGAGVKPWA TYNDSHRQEC DDEMIEVFAV TSSFHIAQMQ IGLASPLCIG 480
  481 QAKHAKLVFK GNHSFPMQSD GEAWVNSAGT VLISHKCKTA MLRKAEKQTT GCGMFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] PSI-BLAST 4.69897 No description for 2db6A was found.
    2 View Details [109..199] PSI-BLAST 22.69897 Crystal Structure of the Human Beta2-Chimaerin
    3 View Details [200..536] PSI-BLAST 24.39794 No description for 2jgrA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.28178434527408 bayes_pls_golite062009
  • protein binding
    		•  0.634132597449966 bayes_pls_golite062009
  • catalytic activity
    		•  0.564904183614451 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.509180585718177 bayes_pls_golite062009
  • kinase activity
    		•  0.502413328106933 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.416811228361087 bayes_pls_golite062009
  • transferase activity
    		•  0.255707908488426 bayes_pls_golite062009
  • protein kinase activity
    		•  0.197456871880971 bayes_pls_golite062009
    3
    Term Confidence Notes
  • kinase activity
    		•  1.93010589087203 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.6993468998669 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.62136531467279 bayes_pls_golite062009
  • transferase activity
    		•  1.1287574677626 bayes_pls_golite062009
  • catalytic activity
    		•  0.704900964793432 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle