Protein Overview: ceh-18

General Information:
Name(s) found:	ceh-18 / CE31263 [WormBase]
Description(s) found: Found 18 descriptions. SHOW ALL	WBGene00000441 locus:ceh-18 status:Confirmed UniProt:Q8MPS1 protein_id:CCD71432.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	540 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][IEA]
Biological Process:	ovulation from ovarian follicle [IMP] oocyte maturation [IMP] embryonic development ending in birth or egg hatching [IMP] epidermis development [IMP] regulation of transcription, DNA-dependent [IEA] germ cell migration [IMP]
Molecular Function:	transcription factor activity [IEA][ISS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTLENTFQF LAEVFEANGG CLVTERVSPS LSGASKRKSR PVKRIITEDE VIPEEEVVEE  60
   61 EEEEKVEQPS EEVTCPAMQV DATDAILASL RQIANNDLSE HCIREDEGNT SAEVFSNGNG 120
  121 EDMEQAGLAG TDLLRRVADM LQGNHNGSLN SHFLQQQFAA FKVDPTPVST NGNGLLTPIT 180
  181 TQLSPLFTST DAFNSPEKLL QAIMTPSLGF LGANGLGASN SGLLSSPLIA PSPTLLQSLM 240
  241 NTPTQPTASL TPKKAENRPP VVSQTLKASK RRLFDDTSRI EAASMSGDDR IDMNELEAFA 300
  301 QTFKKQRIKF GFTQGDVGVA LGKRYGTDFS QTTISRFEAL NLSFKNMCKL RPLLKEWLAD 360
  361 VEMAIEGGAT VTDLIDKKTI HNGNHHTIHH VDIHETSISN SISSVTASSL LSREQHVKRR 420
  421 RKRTNLDMNQ RNALDTFFAL NPRPDHDKMT DIANSLELDR DVVRVWFCNR RQKMRRVDEP 480
  481 IEGEMVTPSV SPVFPHFSSM SALEQIQEAA RLASCQASND DSDGTSGSPD APSNDGCSDL 540
  541

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..72]	deduced	N/A	No confident structure predictions are available.
2	View Details	[73..187]	PSI-BLAST	12.522879	Solution structure of the second CUT domain of human Homeobox protein Cux-2
3	View Details	[188..284]	deduced	N/A	No confident structure predictions are available.
4	View Details	[285..540]	PSI-BLAST	21.0	TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
DNA binding	5.51228466689923	bayes_pls_golite062009
nucleic acid binding	5.37468811865033	bayes_pls_golite062009
transcription regulator activity	5.05236457497789	bayes_pls_golite062009
transcription factor activity	3.89464979825638	bayes_pls_golite062009
binding	3.66501723413351	bayes_pls_golite062009
sequence-specific DNA binding	3.25218945600666	bayes_pls_golite062009
transcription activator activity	3.15886611325686	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.32042014361691	bayes_pls_golite062009
transcription repressor activity	1.75958281319075	bayes_pls_golite062009
protein binding	1.55649304400241	bayes_pls_golite062009
transcription factor binding	1.02788976342343	bayes_pls_golite062009
transcription cofactor activity	0.8718993114781	bayes_pls_golite062009
chromatin binding	0.62573870961765	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.34211447646243	bayes_pls_golite062009
catalytic activity	0.00446472034106909	bayes_pls_golite062009

3

No functions predicted.

4

Term	Confidence	Notes
DNA binding	5.51228466689923	bayes_pls_golite062009
nucleic acid binding	5.37468811865033	bayes_pls_golite062009
transcription regulator activity	5.05236457497789	bayes_pls_golite062009
transcription factor activity	3.89464979825638	bayes_pls_golite062009
binding	3.66501723413351	bayes_pls_golite062009
sequence-specific DNA binding	3.25218945600666	bayes_pls_golite062009
transcription activator activity	3.15886611325686	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.32042014361691	bayes_pls_golite062009
transcription repressor activity	1.75958281319075	bayes_pls_golite062009
protein binding	1.55649304400241	bayes_pls_golite062009
transcription factor binding	1.02788976342343	bayes_pls_golite062009
transcription cofactor activity	0.8718993114781	bayes_pls_golite062009
chromatin binding	0.62573870961765	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.34211447646243	bayes_pls_golite062009
catalytic activity	0.00446472034106909	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.81

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle