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Protein Overview: hum-2

General Information:
Name(s) found: hum-2 / CE30777 [WormBase]
Description(s) found:
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  • WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8MYQ0 protein_id:CCD68603.1 [WormBase]
  • gi|25153899|ref|NP_741590.1| Heavy chain, Unconventional Myosin family member (hum-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|20901964|gb|AAM29688.1|U53181_5 Heavy chain, unconventional myosin protein 2, isoform c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • CE30777 WBGene00002036 locus:hum-2 status:Confirmed TR:Q8MYQ0 protein_id:AAM29688.1 [wormpep150.fasta]
  • 30777 WBGene00002036 locus:hum-2 status:Partially_confirmed TR:Q8MYQ0 protein_id:AAM29688.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • Heavy chain, unconventional myosin protein 2, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • 30777 WBGene00002036 locus:hum-2 status:Confirmed TR:Q8MYQ0 protein_id:AAM29688.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:hum-2 status:Partially_confirmed TR:Q8MYQ0 protein_id:AAM29688.1 [wormpep115.fasta.reversed]
  • CE30777 status:Partially_confirmed [wormpep80.hongbin]
  • CE30777 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8MYQ0_CAEEL protein_id:AAM29688.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE30777 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8MYQ0_CAEEL protein_id:AAM29688.1| [wormORF-contam.fasta]
  • Heavy chain, Unconventional Myosin family member (hum-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE30777 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8MYQ0 protein_id:AAM29688.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE30777 WBGene00002036 locus:hum-2 status:Confirmed UniProt:Q8MYQ0 protein_id:CCD68603.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q17383, Heavy chain, Unconventional Myosin OS=Caenorhabditis elegans GN=hum-2 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 516 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein binding [IPILink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]
    motor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEFDEVGTS TPQPSLKSRM ASAASSDYYC MTFDEPEEMD DVTLSSSATS KRPSDCSLDE  60
   61 AVRGAHKQTQ LLAQQNMDLN DKLTRQSEEL AEARAQLRGY SGPLGLENAS DEEIIRLEAF 120
  121 EKGSIKHSGF LEVYNVPEFA RIIVCELKPT LARLLTKNLP AYLLVAAFRN HDEKRDETAL 180
  181 TGLFSSVHLV LKDTISRSHD LDLLSLWLVN LWRLFNLLRQ YSGEDSQPEW HVANTETQNS 240
  241 YRFKAYDVAP IRDQLKLRIE ECYTSLMKKA IEHVLSPKIV PGILQHESSS DLMTAGQERR 300
  301 DRNSGSVESQ RKSLDDLLQF MEIVHTKLTT YGGDDIVVKQ VIGQMARWMC ALALNYMMFR 360
  361 RELCNFEKAI QIKHNVTQIQ NWLNAKGLSD CRDHFEPLVQ ACHLLQSRKD PSNLDTLCGE 420
  421 MTSRLKPRQV VAILQHYDPS DEMEDGLSPE FLVQIQKKLN ERAIANNDPI EDKDKLIMLG 480
  481 TYLPPFDTQP FSYSDFPLET LSLPSCLHMQ SVCRLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] PSI-BLAST 8.39794 Heavy meromyosin subfragment
    2 View Details [120..516] PSI-BLAST 74.69897 Myosin V cargo binding domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle