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View Structure Prediction Details

Protein: hum-2
Organism: Caenorhabditis elegans
Length: 516 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hum-2.

Description E-value Query
Range
Subject
Range
gi|7441408, gi|2... - pir||T14278 myosin-like protein my4 - common sunflower, gi|2444178|gb|AAB71528.1| unconventional myo...
382.0 [0..2] [509..974]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEFDEVGTS TPQPSLKSRM ASAASSDYYC MTFDEPEEMD DVTLSSSATS KRPSDCSLDE  60
   61 AVRGAHKQTQ LLAQQNMDLN DKLTRQSEEL AEARAQLRGY SGPLGLENAS DEEIIRLEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [120-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEKGSIKHSG FLEVYNVPEF ARIIVCELKP TLARLLTKNL PAYLLVAAFR NHDEKRDETA  60
   61 LTGLFSSVHL VLKDTISRSH DLDLLSLWLV NLWRLFNLLR QYSGEDSQPE WHVANTETQN 120
  121 SYRFKAYDVA PIRDQLKLRI EECYTSLMKK AIEHVLSPKI VPGILQHESS SDLMTAGQER 180
  181 RDRNSGSVES QRKSLDDLLQ FMEIVHTKLT TYGGDDIVVK QVIGQMARWM CALALNYMMF 240
  241 RRELCNFEKA IQIKHNVTQI QNWLNAKGLS DCRDHFEPLV QACHLLQSRK DPSNLDTLCG 300
  301 EMTSRLKPRQ VVAILQHYDP SDEMEDGLSP EFLVQIQKKL NERAIANNDP IEDKDKLIML 360
  361 GTYLPPFDTQ PFSYSDFPLE TLSLPSCLHM QSVCRLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.69897
Match: 2f6hX
Description: Myosin V cargo binding domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle