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Protein Overview: pry-1

General Information:
Name(s) found: pry-1 / CE30125 [WormBase]
Description(s) found:
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  • WBGene00004202 locus:pry-1 Axin-like protein pry-1 status:Confirmed UniProt:O62090 protein_id:CAB07332.2 [WormBase]
  • gi|74960142|sp|O62090.2|PRY1_CAEEL RecName: Full=Axin-like protein pry-1; AltName: Full=Protein polyray [NCBI NR]
  • gi|25150177|ref|NP_493474.2| PolyRaY family member (pry-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|18652358|gb|AAL77082.1|AF468834_1 PRY-1 [Caenorhabditis elegans] [NCBI NR]
  • gi|18376517|emb|CAB07332.2| C. elegans protein C37A5.9, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Axin-like protein pry-1 OS=Caenorhabditis elegans GN=pry-1 PE=1 SV=2 [Swiss-Prot]
  • [wormpep79.fasta]
  • CE30125 WBGene00004202 locus:pry-1 status:Confirmed TR:O62090 protein_id:CAB07332.2 [wormpep150.fasta]
  • 30125 WBGene00004202 locus:pry-1 status:Confirmed TR:O62090 protein_id:CAB07332.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • PolyRaY PRY-1, axin/conductin like (66.0 kD) (pry-1) [Caenorhabditis elegans]gi|18652358|gb|AAL77082.1| PRY-1 [Caenorhabditis elegans]gi|18376517|emb|CAB07332.2| Hypothetical protein C37A5.9 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:pry-1 status:Confirmed TR:O62090 protein_id:CAB07332.2 [wormpep115.fasta.reversed]
  • CE30125 locus:pry-1 status:Confirmed TR:O62090 protein_id:CAB07332.2 [wormpep80.hongbin]
  • CE30125 WBGene00004202 locus:pry-1 status:Confirmed UniProt:O62090_CAEEL protein_id:CAB07332.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE30125 WBGene00004202 locus:pry-1 status:Confirmed UniProt:O62090_CAEEL protein_id:CAB07332.2| [wormORF-contam.fasta]
  • PolyRaY family member (pry-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • PRY-1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C37A5.9 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE30125 WBGene00004202 locus:pry-1 status:Confirmed UniProt:O62090 protein_id:CAB07332.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE30125 WBGene00004202 locus:pry-1 status:Confirmed UniProt:PRY1_CAEEL protein_id:CAB07332.2 [wormbase_c-elegans_197_11-26-2008_reversed.fasta]
  • CE30125 WBGene00004202 locus:pry-1 status:Confirmed UniProt:O62090 protein_id:CAB07332.2 Axin-like protein pry-1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 586 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: negative regulation of vulval development [IGILink to PubMed article][IMPLink to PubMed article]
    embryonic cleavage [IMPLink to PubMed article]
    spindle organization [IMPLink to PubMed article]
    regulation of cell fate specification [IMPLink to PubMed article]
    multicellular organismal development [IEALink to PubMed article]
    anterior/posterior pattern formation [IMPLink to PubMed article]
    negative regulation of Wnt receptor signaling pathway [IGILink to PubMed article]
    cell migration [IMPLink to PubMed article]
    Molecular Function: signal transducer activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METHLGWARS LEAVLSDRSA LDAFQEWLIE YSSPQYLDLF FAIRAYERMA LEGKPEKSQL  60
   61 SKSIYSKFLS SRTGNCEAIP KHFRAPIGEK LRHGTELEDR VFSHCSNFVQ EFLRRQHEEF 120
  121 VGSEEFIEAF NKMSSTTADQ LPGGSAHHSS HQNTMRRSSG TTSRKSAAQI ATQLTAEALL 180
  181 KSKHDRHSKL GETKLEKMYP PTRQPYVCNA TTSHNDSAVS STFSGDTPEA HRMHSNRLRH 240
  241 IRDEQARENH GTMTLPRVEK ASVDGQQWDH SSESGRRNFA MEITRKLLRH IDKVKLNDEM 300
  301 EKRIDDIEEC RYTTIDMVNG TEPNDDLGKI DEDEELDDYL KMKMTDDSQK GSTNRSPKGP 360
  361 AGEPNKSGEG SKNTTLSPTN RAPAQLHNTI RVPRRKDYPR DTSASLKSHR HHQIDTNRMM 420
  421 SQSMCAPSYS SASSSYSRDS FAPAPTTRVN FAPGSSKSSQ FYDSSGIGSM APSAFSATSS 480
  481 LDYKDRRQHR KAPTPKKHSK IGKNLSNLIT ISYLGTDKIP VVTHVPNDGP MTLAEFKRHF 540
  541 ALPNGAHQLF FKTECEDGSA PFQLLLIKDE HHLLPVFEGR IAAELR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] PSI-BLAST 41.0 No description for 2jm5A was found.
    2 View Details [139..276] deduced N/A No confident structure predictions are available.
    3 View Details [277..503] MSA 2.100987 View MSA. No confident structure predictions are available.
    4 View Details [504..586] PSI-BLAST 28.0 Crystal structure of axin dix domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle