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Protein Overview: gpc-2

General Information:
Name(s) found: gpc-2 / CE20656 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00001682 locus:gpc-2 status:Confirmed UniProt:G5ECT6 protein_id:CCD66934.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 62 amino acids

    Gene Ontology:
    Cellular Component: heterotrimeric G-protein complex [IEALink to PubMed article]
    Biological Process: pronuclear migration [IMPLink to PubMed article]
    G-protein coupled receptor protein signaling pathway [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: signal transducer activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKSDMQRTV DSLRSQLNIE RTPITVSAAE LRRFTESQED PLVNPIDKKV NPWAEKSKCS  60
   61 ML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..62] PSI-BLAST 20.0 The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTPase activity
    		•  6.01646376999889 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  2.59868793911346 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  2.59868793911346 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  1.93225355053758 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.86638084591699 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.79571290781105 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.77742639118775 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.77512507657227 bayes_pls_golite062009
  • signal transducer activity
    		•  1.75801578312445 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.75801578312445 bayes_pls_golite062009
  • binding
    		•  1.25375089530994 bayes_pls_golite062009
  • hydrolase activity
    		•  0.692793543292009 bayes_pls_golite062009
  • protein binding
    		•  0.399162858691971 bayes_pls_golite062009
  • receptor binding
    		•  0.38304823982539 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle