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Protein Overview: unc-37

General Information:
Name(s) found: unc-37 / CE14434 [WormBase]
Description(s) found:
Found 25 descriptions.
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  • WBGene00006773 locus:unc-37 Transcription factor unc-37 status:Confirmed UniProt:O02482 protein_id:CCD68992.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 612 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: oocyte construction [IMPLink to PubMed article]
    pronuclear migration [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    regulation of axonogenesis [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    negative regulation of transcription [ISSLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    regulation of neurotransmitter levels [IDALink to PubMed article]
    regulation of synapse structure and activity [IMPLink to PubMed article]
    synaptic transmission [IMPLink to PubMed article]
    Molecular Function: transcription corepressor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASYLETLD RIKDEHAEMS KHVNQQRSDI EKVALEKENM NRSYMTYAEV SNTLRSDLRK  60
   61 AEEINKRLQE FIMQSLAPQL SQDNQANCLA ALEAFKTASP RENGNGAPAL PPGFPPGAAG 120
  121 MLGMMPNMPF GMSPAMSQLF NQFASPHVNG GDGAGGSSGG ASEAKKAKLE DPDDGELEID 180
  181 VTNDDHPSTA SNGGAANKNG RDSTNSVASS GASTPSIASN SRARQQQQPL AGLQGLEQMN 240
  241 FLAGFNPNLL RQASAAGGFN FLNDPHAQAR LAAAIGQIGS RPAYSFKIVD GGVPTPTSFP 300
  301 PDAQKGPGIP TGLKKKMELN HGEVVCAATI SRDNSRVYTG GKGCVKIWDV KESDISGATV 360
  361 VNRPPIASLD CLKENYIRSC KLFEDGNTLL IGGEASTVAL WDLTTETKTL DLETDSQACY 420
  421 ALAMSPDEKL LFACLADGNI LIYDIHNKVK VGTLPGHQDG ASCLDLSKDG TKLWSGGLDN 480
  481 SVRCWDLAQR KEVAKHDFAS QVFSLGCCPN DEWVAVGMEN NYVEVLSTTG KEKYQLTQHE 540
  541 SCVLSLKFAH SGKFFISTGK DNALNAWRTP YGASLFQLKE NSSVLSCDIS FDDSLIVTGS 600
  601 GEKKATLYAV EY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..216] deduced N/A No confident structure predictions are available.
    2 View Details [217..543] PSI-BLAST 50.522879 Cdc4 F-box and linker domains; Cdc4 propeller domain
    3 View Details [544..612] PSI-BLAST 74.09691 Groucho/tle1, C-terminal domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle