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View Structure Prediction Details

Protein: unc-37
Organism: Caenorhabditis elegans
Length: 612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for unc-37.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
563.0 [0..34] [610..1132]

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Predicted Domain #1
Region A:
Residues: [1-216]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASYLETLD RIKDEHAEMS KHVNQQRSDI EKVALEKENM NRSYMTYAEV SNTLRSDLRK  60
   61 AEEINKRLQE FIMQSLAPQL SQDNQANCLA ALEAFKTASP RENGNGAPAL PPGFPPGAAG 120
  121 MLGMMPNMPF GMSPAMSQLF NQFASPHVNG GDGAGGSSGG ASEAKKAKLE DPDDGELEID 180
  181 VTNDDHPSTA SNGGAANKNG RDSTNSVASS GASTPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [217-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IASNSRARQQ QQPLAGLQGL EQMNFLAGFN PNLLRQASAA GGFNFLNDPH AQARLAAAIG  60
   61 QIGSRPAYSF KIVDGGVPTP TSFPPDAQKG PGIPTGLKKK MELNHGEVVC AATISRDNSR 120
  121 VYTGGKGCVK IWDVKESDIS GATVVNRPPI ASLDCLKENY IRSCKLFEDG NTLLIGGEAS 180
  181 TVALWDLTTE TKTLDLETDS QACYALAMSP DEKLLFACLA DGNILIYDIH NKVKVGTLPG 240
  241 HQDGASCLDL SKDGTKLWSG GLDNSVRCWD LAQRKEVAKH DFASQVFSLG CCPNDEWVAV 300
  301 GMENNYVEVL STTGKEKYQL TQHESCV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.522879
Match: 1nexB
Description: Cdc4 F-box and linker domains; Cdc4 propeller domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [544-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSLKFAHSGK FFISTGKDNA LNAWRTPYGA SLFQLKENSS VLSCDISFDD SLIVTGSGEK  60
   61 KATLYAVEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.09691
Match: 1gxrA
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle