Protein Overview: SPAC1565.02c

General Information:
Name(s) found:	SPAC1565.02c [Sanger Pombe]
Description(s) found: Found 18 descriptions. SHOW ALL	GTPase activating protein [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	374 amino acids
Gene Ontology:
Cellular Component:	Golgi apparatus [IDA]
Biological Process:	regulation of Rho GTPase activity [ISS]
Molecular Function:	Rho GTPase activator activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHDLERLCF IGGYDNDNDK VIVVVTKNLE LFKKYDDINL IKEAYNHVHK LIQKDERYTA  60
   61 VFFAHDSTVF SYLGLSLKAY YGMDYYLHKN VKAVYVIHTD WMSKVAIRTL LSIASPKFTR 120
  121 KFRYLNSISD LNKYIPLSHL KLPPIVYEFD RNVEPAIFPS NPSATSNFIF PVQQWTRPPD 180
  181 ALVEGMQVVS KSLQTEGLFR KSCSRKHLDI VIELYDNGCM VDLEAFGPIA ACSLIKHLFR 240
  241 SLPSPLFSAE FLNGLTDHMD SGIDYAVSLQ KLIDASMDKN SQKLARLIFS LLYQITQHEQ 300
  301 ENMMNAQNLA LCIGPSFSKA DNIAELMSMK DKEYNPYCYF LEYAILHWNT LFANEENWDS 360
  361 YIPQDPTLLL PKTP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..97]	PSI-BLAST	20.69897	PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P FROM SACCHAROMYCES CEREVISIAE
2	View Details	[98..374]	PSI-BLAST	37.39794	Crystal Structure of the Human Beta2-Chimaerin

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	2.07778268514777	bayes_pls_golite062009
protein binding	0.385179389448981	bayes_pls_golite062009
retinoid binding	0.364944358872539	bayes_pls_golite062009
isoprenoid binding	0.336310046467439	bayes_pls_golite062009
enzyme regulator activity	0.110690659157048	bayes_pls_golite062009

2

Term	Confidence	Notes
Rho GTPase activator activity	4.58620967349979	bayes_pls_golite062009
Rac GTPase activator activity	4.48279904625182	bayes_pls_golite062009
GTPase regulator activity	2.70614727793157	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	2.68579854252375	bayes_pls_golite062009
binding	2.36195429973813	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	2.06038764955701	bayes_pls_golite062009
enzyme regulator activity	1.9750017471254	bayes_pls_golite062009
small GTPase regulator activity	1.95738547986197	bayes_pls_golite062009
protein binding	1.29100556128076	bayes_pls_golite062009
Ras GTPase activator activity	1.09070479183477	bayes_pls_golite062009
Rho guanyl-nucleotide exchange factor activity	0.967362611034944	bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity	0.958295643211986	bayes_pls_golite062009
GTPase activator activity	0.717730683557543	bayes_pls_golite062009
transcription regulator activity	0.487499907025216	bayes_pls_golite062009
enzyme activator activity	0.298334474872045	bayes_pls_golite062009
Rho GTPase binding	0.150587174126097	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle