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Protein Overview: ste6

General Information:
Name(s) found: ste6 / SPCC1442.01 [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • guanyl-nucleotide exchange factor Ste6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 911 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [IEA]
    conjugation with cellular fusion [IMPLink to PubMed article]
    regulation of catalytic activity [IC]
    Molecular Function: guanyl-nucleotide exchange factor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFQTTAISD YENSSNPSFL KFSAGDTIIV IEVLEDGWCD GICSEKRGWF PTSCIDSSKI  60
   61 QNFFSSFHSS NEKDPNAQCC APFHVEAHLQ DSAWFEKHGV QAINSIPSSE EFLRKNLQND 120
  121 IHHLVKGILT TAAAVSQSIK KEGTQVIVFG IETVRSMVLS FPLIILSTLD ENFLSEVAQV 180
  181 FSSLNLLPEL SRMGCTYGEL CIRFTKLLKQ LANKFLFFFR PDVSFPSYFL GSLIAHEIHF 240
  241 LPWDFNMLCS NSVQSAHTNL QPDITSFVAI LSLSHEAYHC TENEFWNLEA QKLTENTTQK 300
  301 VLQLVAEDAL EAWKLDILED IDRCIQCCRR FLSANQRINY SSSENNPFSF TSQDVEALKD 360
  361 ELSSNLCDLY LWSIDLEQIS PSDCLLDNYS LFVDLLVTLK VSLLRIKSII VQFSERIVFL 420
  421 SLEYKFLTNI QPELNDAEKS QLDGFDLNKT NWFDSKGLVC YLMKQTSPEP LLIRNLLFSF 480
  481 WSCNGKIEQD GKIKTATLVF IINYLLRTDI DSTFFTTIFL NTYASMISSS DLFSILGAHF 540
  541 RFICSLNFGK ISFISHEFYR VSKRFLDILL IWFESYLVEE LDNSKSIFFL FKIYKVFEVF 600
  601 VVPHFASAEE LLHSLSHLLH HPSTKRSHKM LEGKELSQEL EDLSLHNSPD PIIYKDELVL 660
  661 LLPPREIAKQ LCILEFQSFS HISRIQFLTK IWDNLNRFSP KEKTSTFYLS NHLVNFVTET 720
  721 IVQEEEPRRR TNVLAYFIQV CDYLRELNNF ASLFSIISAL NSSPIHRLRK TWANLNSKTL 780
  781 ASFELLNNLT EARKNFSNYR DCLENCVLPC VPFLGVYFTD LTFLKTGNKD NFQNMINFDK 840
  841 RTKVTRILNE IKKFQSVGYM FNPINEVQEL LNEVISRERN TNNIYQRSLT VEPRESEDQA 900
  901 LQRLLIDSGI F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] FFAS03 4.51 Solution structure of the first SH3 domain of human intersectin2 (KIAA1256)
    2 View Details [107..258] deduced N/A No confident structure predictions are available.
    3 View Details [259..911] PSI-BLAST 139.0 Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.01939163574954 bayes_pls_golite062009
  • protein binding
    		•  1.71199213513011 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.169020668544027 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.34731558780557 bayes_pls_golite062009
  • protein binding
    		•  1.90786769159903 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  0.885131503553978 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle