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Protein Overview: rad22

General Information:
Name(s) found: rad22 / SPAC30D11.10 [Sanger Pombe]
Description(s) found:
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  • gi|19114119|ref|NP_593207.1| DNA repair protein Rad22 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1346948|sp|P36592.2|RAD22_SCHPO RecName: Full=DNA repair and recombination protein rad22 [NCBI NR]
  • gi|1065897|emb|CAA91896.1| DNA recombination protein Rad22 [Schizosaccharomyces pombe] [NCBI NR]
  • DNA repair protein Rad22 [Sanger Pombe]
  • DNA repair and recombination protein rad22 OS=Schizosaccharomyces pombe GN=rad22 PE=1 SV=2 [Swiss-Prot]
  • (P36592) DNA repair and recombination protein rad22 [Swiss-Prot]
  • DNA REPAIR AND RECOMBINATION PROTEIN; INVOLVED IN MATING TYPE SWITCHING; SIMILAR TO S. CEREVISIAE RAD52: P36592; [pompepVF.fasta]
  • DNA REPAIR AND RECOMBINATION PROTEIN; INVOLVED IN MATING TYPE SWITCHING: P36592; [pompepV13]
  • DNA repair and recombination protein rad22 [pompep4896]
  • |rad22||DNA repair protein (PMID 8290356) [pompepnew.fasta]
  • |rad22||involved in DNA repair (PMID 8290356)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • |rad22||DNA repair protein Rad22|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • dna repair and recombination protein rad22. [Schizosaccharomyces pombe]gi|1065897|emb|CAA91896.1| SPAC30D11.10 [Schizosaccharomyces pombe]gi|1346948|sp|P36592|RA22_SCHPO DNA repair and recombination protein rad22 [nrdb_11152004_Chlamydomonas]
  • |rad22|rad22A|DNA recombination protein Rad22|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC30D11.10 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC30D11.10 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • |rad52|rad22A, rad22|DNA recombination protein Rad22|Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • DNA repair and recombination protein rad22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rad22 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 469 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IDALink to PubMed article]
    Biological Process: double-strand break repair via homologous recombination [IGILink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    protein homooligomerization [IDALink to PubMed article]
    gene conversion at mating-type locus, DNA repair synthesis [IMPLink to PubMed article]
    meiotic DNA repair synthesis [IMPLink to PubMed article]
    DNA recombinase assembly [NAS]
    mating type switching [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed articleLink to PubMed articleLink to PubMed article]
    damaged DNA binding [TASLink to PubMed article]
    single-stranded DNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFEQKQHVA SEDQGHFNTA YSHEEFNFLQ SSLTRKLGPE YVSRRSGPGG FSVSYIESWK  60
   61 AIELANEIFG FNGWSSSIRS INVDFMDENK ENGRISLGLS VIVRVTIKDG AYHEDIGYGS 120
  121 IDNCRGKASA FEKCKKEGTT DALKRALRNF GNSLGNCMYD KYYLREVGKM KPPTYHFDSG 180
  181 DLFRKTDPAA RESFIKKQKT LNSTRTVNNQ PLVNKGEQLA PRRAAELNDE QTREIEMYAD 240
  241 EELDNIFVED DIIAHLAVAE DTAHPAANNH HSEKAGTQIN NKDKGSHNSA KPVQRSHTYP 300
  301 VAVPQNTSDS VGNAVTDTSP KTLFDPLKPN TGTPSPKFIS ARAAAAAEGV VSAPFTNNFN 360
  361 PRLDSPSIRK TSIIDHSKSL PVQRASVLPI IKQSSQTSPV SNNSMIRDSE SIINERKENI 420
  421 GLIGVKRSLH DSTTSHNKSD LMRTNSDPQS AMRSRENYDA TVDKKAKKG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 80.0 The homologous-pairing domain of Rad52 recombinase
    2 View Details [204..322] MSA 1.173997 View MSA. No confident structure predictions are available.
    3 View Details [323..469] MSA 7.173992 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.14765341131293 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.0351747710117 bayes_pls_golite062009
  • RNA binding
    		•  1.51047378734681 bayes_pls_golite062009
  • protein binding
    		•  1.45612186272752 bayes_pls_golite062009
  • DNA binding
    		•  1.36164279504822 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.01871957569312 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  0.486416546047936 bayes_pls_golite062009
  • transcription factor activity
    		•  0.1846534408189 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.109630981204183 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0240483444006283 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle