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Protein Overview: mis6

General Information:
Name(s) found: mis6 / SPAC1687.20c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • inner centromere protein Mis6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 672 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    inner kinetochore of condensed chromosome [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    condensed chromosome, centromeric region [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Mis6-Sim4 complex [TASLink to PubMed article]
    Biological Process: sister chromatid segregation [IMPLink to PubMed article]
    mitotic spindle organization [IMPLink to PubMed article]
    protein localization to kinetochore [IGILink to PubMed article]
    kinetochore assembly [TASLink to PubMed article]
    CenH3-containing nucleosome assembly at centromere [TASLink to PubMed article]
    cellular protein localization [IGILink to PubMed articleLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESFENKGFL DIEEGIQWIK KNSENLSSSK KTILARLQQF HKLCSEVGLN QHSISSLLDV  60
   61 ILSKKTHFDK NHVQLLIKCL YPNELISQTI AIRIISSLDP HGLRCSYAIQ AKLLNWLIHV 120
  121 YEFLDGNNLL CRYYGVLFHF LDFLTLRPYI SNLLVLLTKH YHVKSFRIHQ LLALYQKPGN 180
  181 TADPYLLALI LTYKQHFPDV IVGSYTYRKH GSVRLDSEWI AATKAILNRQ SEDVPLETWS 240
  241 SEKRKRQSSL IPDLITMKNT SSSYSLEELT SVQQMGLVYE KIVFPSRIAA VLKSKLFLIF 300
  301 LFLKNKNVYY SRLDEWLHIT LNYGLALRSG SNNQEEEVLH LLYKYLLFSP KFPKSLLQYV 360
  361 ITFFSKPNIT EENYNLLTLL VTHIPITTDS SYFNSLLKEF EQFILQKNAE FCSKHLNILW 420
  421 LWLFRMLNLR IASMGNNHTL LEKCLLITNH ATFLVSHFSW DVSLAYQLSR LFQLYYKILT 480
  481 KIRKQIEPNI PPKELIYVLF FQPSAFYINS MVGLLLLTKN YQERLMDSRI DAISKFTHSY 540
  541 LKSLSEIILL KEKRAILSFL QLWEPFKSDY SQFLPIATRI ANDHPYAQRV FSLTCAPQFF 600
  601 SYINGYQIYL QQTNPATGSI PLKPIQEETF GAFQSNLHLS DSWEDFQKNF IIYLKKKGYL 660
  661 AISDFLLSTL NR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239] deduced N/A No confident structure predictions are available.
    2 View Details [240..436] deduced N/A No confident structure predictions are available.
    3 View Details [437..543] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [544..672] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle