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Protein Overview: trem-PA

General Information:
Name(s) found: trem-PA / FBpp0083249 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene trade embargo is referred to in FlyBase by the symbol Dmel\trem (CG4413, FBgn0038767). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15855282..15857025. It has the cytological map location 92C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: reciprocal meiotic recombination; meiosis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: reciprocal meiotic recombination [IMP]
    meiosis [IMP]
    Molecular Function: nucleic acid binding [IEA]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTESNEKWV VCRVCLNNPS EGEELLHDIF SETASTRLDQ MLHICAGIPV SLDDNFPDKM  60
   61 CSKCVRCLRL CYKFRLTCQR SHQHIMDMLD REASNANAAG EGDLLSIAED LSVESVLKSW 120
  121 EDYASQLDGG MKVEGEEDQQ HQVITYVVED GDTDDTNMFD VHDPTQPVPN EIEEAETYAE 180
  181 YEEYELLTNE NSPEIAQEKG STGTDVATEE PPEEEIAEDI LDSDEDYDPT HAKPEKCDRS 240
  241 GRKPVAYHKN SPKVETFKKK VGRKPRNKLS TYICDVCGNI YPTQARLTEH MKFHSGVKPH 300
  301 ECEICGRGFV QNQQLVRHMN THTGNRPYKC NYCPAAFADR STKTKHHRIH TKERPYVCDV 360
  361 CSRTFTYSDN LKFHKMIHTG EKPHVCDLCG KGFVKAYKLR LHRETHNRRI TWRNDAEEST 420
  421 KAEDVKGETP EFLNELPKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] FFAS03 3.08 Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone
    2 View Details [114..204] MSA 2.379992 View MSA. No confident structure predictions are available.
    3 View Details [205..439] PSI-BLAST 61.09691 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.27558039325716 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.04365369058994 bayes_pls_golite062009
  • DNA binding
    		•  2.03081693058447 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.91890460542409 bayes_pls_golite062009
  • protein binding
    		•  1.64123046790677 bayes_pls_golite062009
  • transcription factor activity
    		•  1.28005240080126 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.531420912328414 bayes_pls_golite062009
  • transcription activator activity
    		•  0.448420149095895 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.338250967854476 bayes_pls_golite062009
  • transcription factor binding
    		•  0.25088296722645 bayes_pls_golite062009
  • catalytic activity
    		•  0.133319360419662 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  0.0760964730095472 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle